Antimicrobial materials and devices for biomedical applications

Frontiers in Clinical Drug Research: Anti-Infectives

dc.contributorUR-RAHMAN, ATTA
dc.creatorLOPEZ-SAUCEDO, FELIPE
dc.creatorFLORES-ROJAS, GUADALUPE G.
dc.creatorVARCA, JUSTINE P.R.O.
dc.creatorVARCA, GUSTAVO H.C.
dc.creatorBUCIO, EMILIO
dc.date2020
dc.date2021-03-25T17:43:19Z
dc.date2021-03-25T17:43:19Z
dc.date.accessioned2023-09-28T14:18:19Z
dc.date.available2023-09-28T14:18:19Z
dc.identifierhttp://repositorio.ipen.br/handle/123456789/31955
dc.identifier6
dc.identifier10.2174/9789811425745120060005
dc.identifier3
dc.identifier0000-0002-6545-237X
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/9002178
dc.descriptionBioaccumulation in sanitary devices, caused by opportunistic pathogens, intervenes negatively in the recovery of a patient since these are able to provoke a mild or life-threatening infection. Thus, surfaces of certain materials such as gauzes, catheters, sutures, etc., which are adjacent or directly exposed to a healing zone, are prone to become sites for the growth, proliferation, and spread of pathogenic microorganisms. Although in surgical or healing processes, sterile materials are usually applied, the time of contact with biological interfaces is long enough to make the sterilization but not enough to control and prevent an infection since pathogens abound in the surroundings. Air, water, and soil can be potential vectors, without considering those factors related to iatrogenesis that also play a role in the opportunities for the patient's recovery. Within this context, engineered materials are currently being developed and explored towards devices and biomaterials with improved design, performance, duration, biocompatibility aiming to be safer for the user. The surface functionalization of materials with antimicrobial agents is a highlighted alternative to overcome this issue. This chapter addresses current antimicrobial materials, as well as strategies for obtaining antimicrobial surfaces and coating as well as their properties. In addition, the safety assessment of biomedical applications and international standards are discussed.
dc.format78-126
dc.publisherBentham Science Publishers
dc.rightsclosedAccess
dc.subjectsafety analysis
dc.subjectrisk assessment
dc.subjectantimicrobial agents
dc.subjectcoatings
dc.subjectsurface properties
dc.subjectstandardization
dc.titleAntimicrobial materials and devices for biomedical applications
dc.titleFrontiers in Clinical Drug Research: Anti-Infectives
dc.typeCap??tulo de livro
dc.coverageI
dc.localSingapore


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