| dc.creator | Romero-González, Roberto | |
| dc.creator | Alves, Renata Domingos | |
| dc.creator | López-Ruiz, Rosalía | |
| dc.creator | Jiménez-Medina, M. L. | |
| dc.creator | Frenich, Antonia Garrido | |
| dc.date | 2018-05-10T16:53:16Z | |
| dc.date | 2018-05-10T16:53:16Z | |
| dc.date | 2016-09-05 | |
| dc.date.accessioned | 2023-09-27T21:56:31Z | |
| dc.date.available | 2023-09-27T21:56:31Z | |
| dc.identifier | 16182650 | |
| dc.identifier | http://dx.doi.org/10.1007/s00216-016-9912-2 | |
| dc.identifier | http://www.locus.ufv.br/handle/123456789/19462 | |
| dc.identifier.uri | https://repositorioslatinoamericanos.uchile.cl/handle/2250/8968404 | |
| dc.description | An analytical method based on a modified QuPPe (quick polar pesticide) extraction procedure coupled with liquid chromatography-tandem mass spectrometry (LC-MS/MS)
was evaluated for the determination of four polar compounds
(chlorate, fosetyl-Al, maleic hydrazide, and perchlorate) in
nutraceutical products obtained from soy. Experimental con-
ditions including extraction such as solvent, acidification,
time, and clean-up sorbents were varied. Acidified acetonitrile
(1 % formic acid, v/v) was used as extraction solvent instead of
methanol (conventional QuPPe), which provides a doughy
mixture which cannot be injected into the LC. Clean-up or
derivatization steps were avoided. For analysis, several sta-
tionary phases were evaluated and Hypercarb (porous graphit-
ic carbon) provided the best results. The optimized method
was validated and recoveries ranged between 46 and 119 %,
and correction factors can be used for quantification purposes
bearing in mind that inter-day precision was equal to or lower
than 17 %. Limits of quantification (LOQs) ranged from 4 to
100 μg kg^−1. Soy-based nutraceutical products were analyzed
and chlorate was detected in five samples at concentrations
between 63 and 1642 μg kg^−1. | |
| dc.format | pdf | |
| dc.format | application/pdf | |
| dc.language | eng | |
| dc.publisher | Analytical and Bioanalytical Chemistry | |
| dc.relation | v. 408, n. 28, p. 8089–8098, Novembro 2016 | |
| dc.rights | Springer-Verlag Berlin Heidelberg | |
| dc.subject | Nutraceuticals | |
| dc.subject | Soy | |
| dc.subject | Polar compounds | |
| dc.subject | QuPPe | |
| dc.subject | Liquid chromatography | |
| dc.subject | Mass spectrometry | |
| dc.title | Fast determination of four polar contaminants in soy nutraceutical products by liquid chromatography coupled to tandem mass spectrometry | |
| dc.type | Artigo | |
