Calix[n]arenes: active organocatalysts for the synthesis of densely functionalized piperidines by one-pot multicomponent procedure

dc.creatorLiberto, N.
dc.creatorPalermo, V.
dc.creatorSathicq, A.
dc.creatorFernandes, S.
dc.creatorLanger, P.
dc.creatorJios, J.
dc.creatorRomanelli, G.
dc.date2018-08-22T17:48:46Z
dc.date2018-08-22T17:48:46Z
dc.date2016-05-11
dc.date.accessioned2023-09-27T20:52:42Z
dc.date.available2023-09-27T20:52:42Z
dc.identifier00404039
dc.identifierhttps://doi.org/10.1016/j.tetlet.2016.03.090
dc.identifierhttp://www.locus.ufv.br/handle/123456789/21315
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8949973
dc.descriptionAn efficient, suitable and high yielding method has been developed for the synthesis of different densely functionalized piperidine derivatives via pseudo-five component, one-pot domino reaction through a combination of b-ketoesters, aromatic aldehydes, and various amines using p-sulfonic acid calix[n]arenes as catalysts. The reaction was carried out in refluxing methanol, affording very good yields of the expected piperidine. Atomic economy, environmentally benign procedure, reuse of catalysts, and short reaction time are some of the important features of this protocol.
dc.formatpdf
dc.formatapplication/pdf
dc.languageeng
dc.publisherTetrahedron Letters
dc.relationv. 57, n. 19, p. 2049- 2054, mai. 2016
dc.rightsElsevier Ltd
dc.subjectDensely functionalized piperidines
dc.subjectp-Sulfonic acid calix[n]arenes
dc.subjectHeterocyclic
dc.subjectMulticomponent reactions
dc.subjectOrganocatalysts
dc.titleCalix[n]arenes: active organocatalysts for the synthesis of densely functionalized piperidines by one-pot multicomponent procedure
dc.typeArtigo


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