dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorSalgado, Breno S.
dc.creatorMonteiro, Lidianne N.
dc.creatorColodel, Márcia M.
dc.creatorFigueiroa, Fernanda C.
dc.creatorNonogaki, Suely
dc.creatorRocha, Rafael M.
dc.creatorRocha, Noeme Sousa
dc.date2014-05-27T11:26:51Z
dc.date2016-10-25T18:37:26Z
dc.date2014-05-27T11:26:51Z
dc.date2016-10-25T18:37:26Z
dc.date2012-07-01
dc.date.accessioned2017-04-06T01:59:20Z
dc.date.available2017-04-06T01:59:20Z
dc.identifierComparative Clinical Pathology, v. 21, n. 4, p. 495-499, 2012.
dc.identifier1618-5641
dc.identifier1618-565X
dc.identifierhttp://hdl.handle.net/11449/73398
dc.identifierhttp://acervodigital.unesp.br/handle/11449/73398
dc.identifier10.1007/s00580-012-1516-4
dc.identifier2-s2.0-84864489982
dc.identifierhttp://dx.doi.org/10.1007/s00580-012-1516-4
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/894206
dc.descriptionThis case report describes a case of a mammary invasive pleomorphic lobular carcinoma in a female dog. Cytology revealed small cohesive clusters of cells and many scattered single large round cells with eccentric nuclei. Histologically, the neoplasm presented plasmacytoid cells with multiple, often bizarre nuclei and an invasive pattern with cells occasionally arranged in Indian files. Vascular invasion was consistently present. Tumour cells also revealed loss of E-cadherin immunoexpression and positive immunoreactivity for HER2/c-erbB2, oestrogen receptor alpha, cytokeratin 19, and Ki67 (52 %), and the tumour was characterised as a mammary invasive pleomorphic lobular carcinoma. This is an interesting case since this is a rare condition that is not widely recognised in dogs. © 2012 Springer-Verlag London Limited.
dc.languageeng
dc.relationComparative Clinical Pathology
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectc-ErbB2
dc.subjectCytodiagnosis
dc.subjectCytokeratin 19
dc.subjectE-cadherin
dc.subjectMammary lobular carcinoma
dc.subjectMammary neoplasms
dc.subjectOestrogen receptor alpha
dc.titleCytohistological and immunohistochemical features of a mammary invasive pleomorphic lobular carcinoma in a dog
dc.typeOtro


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