Determinação da toxicidade do selênio por meio de análises hematológicas em Oreochromis niloticus

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorSeriani, Robson
dc.creatorRanzani-Paiva, Maria José Tavares
dc.creatorGonçalves, Adriano
dc.creatorSiqueira, Silmara Regina
dc.creatorLombardi, Julio Vicente
dc.date2014-05-27T11:26:27Z
dc.date2016-10-25T18:36:59Z
dc.date2014-05-27T11:26:27Z
dc.date2016-10-25T18:36:59Z
dc.date2012-04-04
dc.date.accessioned2017-04-06T01:58:13Z
dc.date.available2017-04-06T01:58:13Z
dc.identifierActa Scientiarum - Biological Sciences, v. 34, n. 2, p. 125-131, 2012.
dc.identifier1679-9283
dc.identifier1807-863X
dc.identifierhttp://hdl.handle.net/11449/73283
dc.identifierhttp://acervodigital.unesp.br/handle/11449/73283
dc.identifier10.4025/actascibiolsci.v34i2.8755
dc.identifier2-s2.0-84859205266.pdf
dc.identifier2-s2.0-84859205266
dc.identifierhttp://dx.doi.org/10.4025/actascibiolsci.v34i2.8755
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/894100
dc.descriptionSelenium (Se) is described as an essential micronutrient and participates in different biological functions, as the antioxidant defense systems maintenance and regulation. However, when in high concentrations, Se may cause toxic effects as well as hematological changes in fish. The aim of the present study was to determine the toxicity of selenium in the form of sodium selenate (Na 2Se 6+O 4) in Oreochromis niloticus based on hematological parameters, after exposure to different concentrations (0.01, 0.14 and 1.4 mg Se 6+ L -1). The erythrocytic and leukocytic series were examined over 14 days at intervals of 0, 3, 5, 7,10 and 14 days. The erythrocytic series showed significant alterations in the first 7 days, including the control group. Neutrophils and monocytes showed variations in the first 3 days at a concentration of 1.40 mgSe 6+ L -1 characterizing an acute response. The total number of leukocytes was different in relation to time zero on all Se concentrations. The thrombocyte count also differed statistically from time zero and control in the first 3 days at 0.14 mgSe 6+ L -1. These results indicate that different concentrations induce an acute response with diminution of total leukocytes, neutrophilia, monocytosis and thrombocytosis.
dc.languageeng
dc.languagepor
dc.relationActa Scientiarum: Biological Sciences
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectHaematological
dc.subjectSelenium
dc.subjectToxicity
dc.subjectWater pollution
dc.subjectselenate
dc.subjectacute toxicity
dc.subjectanimal cell
dc.subjectanimal experiment
dc.subjectanimal model
dc.subjectblood toxicity
dc.subjectcell transformation
dc.subjectconcentration response
dc.subjectcontrolled study
dc.subjecterythrocyte
dc.subjecthematological parameters
dc.subjectleukocyte
dc.subjectleukocyte count
dc.subjectmonocyte
dc.subjectmonocytosis
dc.subjectneutrophil
dc.subjectneutrophilia
dc.subjectnonhuman
dc.subjectOreochromis niloticus
dc.subjectselenium toxicity
dc.subjectthrombocyte count
dc.subjectthrombocytosis
dc.subjecttoxicity
dc.subjecttoxicity testing
dc.titleDeterminação da toxicidade do selênio por meio de análises hematológicas em Oreochromis niloticus
dc.typeOtro


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