Towards a post-traumatic subtype of obsessive-compulsive disorder
Journal of Anxiety Disorders, v. 26, n. 2, p. 377-383, 2012.
Fontenelle, Leonardo F.
Harrison, Ben J.
Shavitt, Roseli G.
do Rosário, Maria Conceição
Ferrão, Ygor A.
de Mathis, Maria Alice
Cordioli, Aristides V.
Mari, Jair de Jesus
Miguel, Euripedes C.
Torres, Albina Rodrigues
We evaluated whether traumatic events are associated with a distinctive pattern of socio-demographic and clinical features of obsessive-compulsive disorder (OCD). We compared socio-demographic and clinical features of 106 patients developing OCD after post-traumatic stress disorder (PTSD; termed post-traumatic OCD), 41 patients developing OCD before PTSD (pre-traumatic OCD), and 810 OCD patients without any history of PTSD (non-traumatic OCD) using multinomial logistic regression analysis. A later age at onset of OCD, self-mutilation disorder, history of suicide plans, panic disorder with agoraphobia, and compulsive buying disorder were independently related to post-traumatic OCD. In contrast, earlier age at OCD onset, alcohol-related disorders, contamination-washing symptoms, and self-mutilation disorder were all independently associated with pre-traumatic OCD. In addition, patients with post-traumatic OCD without a previous history of obsessive-compulsive symptoms (OCS) showed lower educational levels, greater rates of contamination-washing symptoms, and more severe miscellaneous symptoms as compared to post-traumatic OCD patients with a history of OCS. © 2011 Elsevier Ltd.
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Federal University of Rio de Janeiro; Fluminense Federal University; University of Melbourne and Melbourne Health; Universidade de São Paulo (USP); Health Sciences Federal University of Porto Alegre; Federal University of Rio Grande do Sul; Universidade Estadual Paulista (UNESP) (2012-03-01)We evaluated whether traumatic events are associated with a distinctive pattern of socio-demographic and clinical features of obsessive-compulsive disorder (OCD). We compared socio-demographic and clinical features of 106 ...
Fontenelle, Leonardo F.; Cocchi, Luca; Harrison, Ben J.; Miguel, Euripedes C.; Torres, Albina Rodrigues
Universidade Federal do Rio de Janeiro (UFRJ); Universidade Federal Fluminense (UFF); University of Melbourne and Melbourne Health; Universidade de São Paulo (USP); Universidade Estadual Paulista (UNESP) (2011-02-01)Whilst genetic factors are thought to contribute to the development of obsessive-compulsive disorder (OCD), the role of environmental factors in OCD is only beginning to be understood. In this article, we review the influence ...