First defection of the equine herpesvirus 1 neuropathogenic variant in Brazil

Mori, E.; Borges, Alexandre Secorun; Delfiol, D. J Z; Oliveira Filho, José Paes de; Goncalves, Roberto Calderon; Cagnini, D. Q.; Lara, M. C C S H; Cunha, E. M S; Villalobos, E. M C; Nassar, A. F C; Castro, A. M M G; Brandao, P. E.; Richtzenhain, L. J.

Otro

Registro en:

OIE Revue Scientifique et Technique, v. 30, n. 3, p. 949-954, 2011.

0253-1933

1608-0645

http://hdl.handle.net/11449/73037

http://acervodigital.unesp.br/handle/11449/73037

2-s2.0-84857272579

http://repositorioslatinoamericanos.uchile.cl/handle/2250/893866

Autor

Mori, E.

Borges, Alexandre Secorun

Delfiol, D. J Z

Oliveira Filho, José Paes de

Goncalves, Roberto Calderon

Cagnini, D. Q.

Lara, M. C C S H

Cunha, E. M S

Villalobos, E. M C

Nassar, A. F C

Castro, A. M M G

Brandao, P. E.

Richtzenhain, L. J.

Institución

Universidade Paulista Júlio de Mesquita Filho (Brasil)

Resumen

This report describes the first detection of an equine herpesvirus 1 (EHV-1) neuropathogenic variant (G 2254/D 752) in Brazil from a case of fatal equine herpesvirus myeloencephalopathy (EHM) in a mare. The results of nucleotide sequencing of the EHV-1 ORF30 gene showed that two other Brazilian EHV-1 isolates from EHM cases are representatives of the non-neuropathogenic variant (A 2254/N 752), suggesting that other unidentified factors are probably also involved in the neuropathogenicity of EHV-1 in horses. These findings will contribute to the epidemiological knowledge of EHV-1 infection in Brazil.

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