Perfusão cerebral e análise individual automatizada utilizando SPECT em uma população com transtorno obsessivo-compulsivo

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorda Rocha, Euclides Timóteo
dc.creatorBuchpiguel, Carlos Alberto
dc.creatorMiguel, Euripedes Constantino
dc.creatorPeres, Stela Verzinhase
dc.creatorFilho, Geraldo Busatto
dc.date2014-05-27T11:25:51Z
dc.date2016-10-25T18:33:49Z
dc.date2014-05-27T11:25:51Z
dc.date2016-10-25T18:33:49Z
dc.date2011-04-26
dc.date.accessioned2017-04-06T01:50:09Z
dc.date.available2017-04-06T01:50:09Z
dc.identifierJornal Brasileiro de Psiquiatria, v. 60, n. 1, p. 1-6, 2011.
dc.identifier0047-2085
dc.identifier1982-0208
dc.identifierhttp://hdl.handle.net/11449/72391
dc.identifierhttp://acervodigital.unesp.br/handle/11449/72391
dc.identifier10.1590/S0047-20852011000100001
dc.identifierS0047-20852011000100001
dc.identifier2-s2.0-79955047693.pdf
dc.identifier2-s2.0-79955047693
dc.identifierhttp://dx.doi.org/10.1590/S0047-20852011000100001
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/893262
dc.descriptionObjective: To make individual assessments using automated quantification methodology in order to screen for perfusion abnormalities in cerebral SPECT examinations among a sample of subjects with OCD. Methods: Statistical parametric mapping (SPM) was used to compare 26 brain SPECT images from patients with OCD individually with an image bank of 32 normal subjects, using the statistical threshold of p < 0.05 (corrected for multiple comparisons at the level of individual voxels or clusters). The maps were analyzed, and regions presenting voxels that remained above this threshold were sought. results: Six patients from a sample of 26 OCD images showed abnormalities at cluster or voxel level, considering the criteria described above, which represented 23.07%. However, seven images from the normal group of 32 were also indicated as cases of perfusional abnormality, representing 21.8% of the sample. Conclusion: The automated quantification method was not considered to be a useful tool for clinical practice, for analyses complementary to visual inspection.
dc.languagepor
dc.relationJornal Brasileiro de Psiquiatria
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectBrain SPECT
dc.subjectIndividual analysis
dc.subjectOCD
dc.subjectSPM
dc.subjectcysteine ethyl ester tc 99m
dc.subjectadult
dc.subjectautomation
dc.subjectbrain mapping
dc.subjectbrain perfusion
dc.subjectclinical article
dc.subjectclinical assessment
dc.subjectcontrolled study
dc.subjectfemale
dc.subjecthuman
dc.subjectimage processing
dc.subjectmale
dc.subjectobsessive compulsive disorder
dc.subjectprediction
dc.subjectsingle photon emission computer tomography
dc.titlePerfusão cerebral e análise individual automatizada utilizando SPECT em uma população com transtorno obsessivo-compulsivo
dc.typeOtro


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