Temporal localization of osteocalcin protein during healing of tooth extraction sockets in rats.

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorRodrigues Luvizuto, E.
dc.creatorMônica Dias, S.
dc.creatorChiantelli Cláudio-Coutinho, C.
dc.creatorAlves Machado, L.
dc.creatorRangel Garcia-Júnior, I.
dc.creatorOkamoto, T.
dc.creatorOkamoto, Roberta
dc.date2014-05-27T11:24:42Z
dc.date2016-10-25T18:28:41Z
dc.date2014-05-27T11:24:42Z
dc.date2016-10-25T18:28:41Z
dc.date2010-06-01
dc.date.accessioned2017-04-06T01:41:28Z
dc.date.available2017-04-06T01:41:28Z
dc.identifierMinerva stomatologica, v. 59, n. 6, p. 355-361, 2010.
dc.identifier0026-4970
dc.identifierhttp://hdl.handle.net/11449/71711
dc.identifierhttp://acervodigital.unesp.br/handle/11449/71711
dc.identifier2-s2.0-79952114123
dc.identifierhttp://www.minervamedica.it/en/journals/minerva-stomatologica/article.php?cod=R18Y2010N06A0355
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/892654
dc.descriptionThe aim of this study was to evaluate the expression of osteocalcin protein during the alveolar bone healing process in rats. Twenty four rats were used in this study and, after anesthetic induction, they had their right upper incisors extracted. At 7, 14, 21 and 28 days after the tooth extraction, the animals were injected 4% formaldehyde. The histological tissue pieces were colored in hematoxilin and eosin and the immunohistochemistry reaction for osteocalcin was performed. At seven days lesser neoformed trabeculae bone and a small quantity of osteocalcin labeling were observed. At 14 and 21 days a larger quantity of neoformed trabeculae bone and higher osteocalcin values were detected. At 28 days the largest quantity of neoformed trabeculae bone and a decrease on the amount of osteocalcin immunolabelling were noticed. According to our results and considering the limits of the present study it is possible to conclude that a greater osteocalcin expression is observed at 14 and 21 days postoperatively, characterizing the periods when intense mineralization of the bone tissue occurs during the alveolar bone healing process.
dc.languageeng
dc.relationMinerva stomatologica
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectosteocalcin
dc.subjectanimal
dc.subjectchemistry
dc.subjectmale
dc.subjectrat
dc.subjecttime
dc.subjecttooth extraction
dc.subjecttooth socket
dc.subjectWistar rat
dc.subjectwound healing
dc.subjectAnimals
dc.subjectMale
dc.subjectOsteocalcin
dc.subjectRats
dc.subjectRats, Wistar
dc.subjectTime Factors
dc.subjectTooth Extraction
dc.subjectTooth Socket
dc.subjectWound Healing
dc.titleTemporal localization of osteocalcin protein during healing of tooth extraction sockets in rats.
dc.typeOtro


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