Algebraic approach to optimal clone selection applied in metagenomic projects

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorCantão, Mauricio E.
dc.creatorDe Araújo, Luciano V.
dc.creatorLemos, Eliana G. M.
dc.creatorFerreira, João E.
dc.date2014-05-27T11:24:41Z
dc.date2016-10-25T18:28:39Z
dc.date2014-05-27T11:24:41Z
dc.date2016-10-25T18:28:39Z
dc.date2010-05-03
dc.date.accessioned2017-04-06T01:41:19Z
dc.date.available2017-04-06T01:41:19Z
dc.identifierISB 2010 Proceedings - International Symposium on Biocomputing.
dc.identifierhttp://hdl.handle.net/11449/71685
dc.identifierhttp://acervodigital.unesp.br/handle/11449/71685
dc.identifier10.1145/1722024.1722066
dc.identifier2-s2.0-77951585495
dc.identifierhttp://dx.doi.org/10.1145/1722024.1722066
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/892634
dc.descriptionDue to the wide diversity of unknown organisms in the environment, 99% of them cannot be grown in traditional culture medium in laboratories. Therefore, metagenomics projects are proposed to study microbial communities present in the environment, from molecular techniques, especially the sequencing. Thereby, for the coming years it is expected an accumulation of sequences produced by these projects. Thus, the sequences produced by genomics and metagenomics projects present several challenges for the treatment, storing and analysis such as: the search for clones containing genes of interest. This work presents the OCI Metagenomics, which allows defines and manages dynamically the rules of clone selection in metagenomic libraries, thought an algebraic approach based on process algebra. Furthermore, a web interface was developed to allow researchers to easily create and execute their own rules to select clones in genomic sequence database. This software has been tested in metagenomic cosmid library and it was able to select clones containing genes of interest. Copyright 2010 ACM.
dc.languageeng
dc.relationISB 2010 Proceedings - International Symposium on Biocomputing
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectMetagenomics
dc.subjectNPWS
dc.subjectOptimal clones
dc.subjectProcess algebra
dc.subjectScientific workflow
dc.subjectAlgebraic approaches
dc.subjectClone selection
dc.subjectCulture medium
dc.subjectGenomic sequence database
dc.subjectGenomics
dc.subjectMetagenomic libraries
dc.subjectMicrobial communities
dc.subjectMolecular techniques
dc.subjectProcess algebras
dc.subjectScientific workflows
dc.subjectWeb interface
dc.subjectCloning
dc.subjectGenes
dc.subjectManagement
dc.subjectOptimization
dc.subjectSoot blowers
dc.subjectAlgebra
dc.titleAlgebraic approach to optimal clone selection applied in metagenomic projects
dc.typeOtro


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