Obsessive-compulsive disorder: Influence of age at onset on comorbidity patterns

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorde Mathis, Maria Alice
dc.creatordo Rosario, Maria Conceição
dc.creatorDiniz, Juliana Belo
dc.creatorTorres, Albina Rodrigues
dc.creatorShavitt, Roseli Gedanki
dc.creatorFerrão, Ygor Arzeno
dc.creatorFossaluza, Victor
dc.creatorde Bragança Pereira, Carlos Alberto
dc.creatorMiguel, Eurípedes Constantino
dc.date2014-05-27T11:23:30Z
dc.date2016-10-25T18:25:23Z
dc.date2014-05-27T11:23:30Z
dc.date2016-10-25T18:25:23Z
dc.date2008-04-01
dc.date.accessioned2017-04-06T01:30:27Z
dc.date.available2017-04-06T01:30:27Z
dc.identifierEuropean Psychiatry, v. 23, n. 3, p. 187-194, 2008.
dc.identifier0924-9338
dc.identifierhttp://hdl.handle.net/11449/70359
dc.identifierhttp://acervodigital.unesp.br/handle/11449/70359
dc.identifier10.1016/j.eurpsy.2008.01.002
dc.identifier2-s2.0-40849101522
dc.identifierhttp://dx.doi.org/10.1016/j.eurpsy.2008.01.002
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/891472
dc.descriptionPurpose: This study investigates the influence of age at onset of OCS on psychiatric comorbidities, and tries to establish a cut-off point for age at onset. Methods: Three hundred and thirty OCD patients were consecutively recruited and interviewed using the following structured interviews: Yale-Brown Obsessive Compulsive Scale; Yale Global Tic Severity Scale and the Structured Clinical Interview for DSM-IV. Data were analyzed with regression and cluster analysis. Results: Lower age at onset was associated with a higher probability of having comorbidity with tic, anxiety, somatoform, eating and impulse-control disorders. Longer illness duration was associated with lower chance of having tics. Female gender was associated with anxiety, eating and impulse-control disorders. Tic disorders were associated with anxiety disorders and attention-deficit/hyperactivity disorder. No cut-off age at onset was found to clearly divide the sample in homogeneous subgroups. However, cluster analyses revealed that differences started to emerge at the age of 10 and were more pronounced at the age of 17, suggesting that these were the best cut-off points on this sample. Conclusions: Age at onset is associated with specific comorbidity patterns in OCD patients. More prominent differences are obtained when analyzing age at onset as an absolute value. © 2008 Elsevier Masson SAS. All rights reserved.
dc.languageeng
dc.relationEuropean Psychiatry
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectAge at onset
dc.subjectComorbidity
dc.subjectEarly onset
dc.subjectLate onset
dc.subjectObsessive-compulsive disorder
dc.subjectadult
dc.subjectage distribution
dc.subjectanxiety disorder
dc.subjectattention deficit disorder
dc.subjectcluster analysis
dc.subjectcomorbidity
dc.subjectdiagnostic and statistical manual of mental disorders
dc.subjectdisease association
dc.subjectdisease duration
dc.subjecteating disorder
dc.subjectfemale
dc.subjecthuman
dc.subjectimpulse control disorder
dc.subjectmajor clinical study
dc.subjectmale
dc.subjectmental patient
dc.subjectobsessive compulsive disorder
dc.subjectonset age
dc.subjectpriority journal
dc.subjectpsychologic test
dc.subjectpsychological rating scale
dc.subjectregression analysis
dc.subjectsomatoform disorder
dc.subjectstructured interview
dc.subjecttic
dc.subjectAdult
dc.subjectAge of Onset
dc.subjectAnxiety Disorders
dc.subjectAttention Deficit Disorder with Hyperactivity
dc.subjectBrazil
dc.subjectCross-Sectional Studies
dc.subjectEating Disorders
dc.subjectFemale
dc.subjectHumans
dc.subjectImpulse Control Disorders
dc.subjectMale
dc.subjectMental Disorders
dc.subjectMiddle Aged
dc.subjectObsessive-Compulsive Disorder
dc.subjectPersonality Assessment
dc.subjectSex Factors
dc.subjectSomatoform Disorders
dc.subjectTic Disorders
dc.titleObsessive-compulsive disorder: Influence of age at onset on comorbidity patterns
dc.typeOtro


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