Article
Campylobacter coli isolated in Brazil typed by core genome Multilocus Sequence Typing shows high genomic diversity in a global context
Registro en:
GOMES, Carolina Nogueira et al. Campylobacter coli isolated in Brazil typed by core genome Multilocus Sequence Typing shows high genomic diversity in a global context. Infection, Genetics and Evolution, v. 95, 105018, p. 1 - 8, 2021.
1567-1348
10.1016/j.meegid.2021.105018
Autor
Gomes, Carolina Nogueira
Barker, Dillon Oliver Reese
Duque, Sheila da Silva
Che, Emily Victoria
Jayamanna, Vasena
Taboada, Eduardo Napoleon
Falcão, Juliana Pfrimer
Resumen
Campylobacter has been one of the most common causative agent of bacterial food-borne gastroenteritis in
humans worldwide. However, in Brazil the campylobacteriosis has been a neglected disease and there is
insufficient data to estimate the incidence of this pathogen in the country.
Aims: The current study aimed to determine the phylogenetic relationships among Campylobacter coli strains
isolated in Brazil and to compare them with international Campylobacter isolates available in some public
databases.
Methods and results: A total of 63C. coli strains isolated in Brazil were studied. The MLST analysis showed 18
different STs including three STs not yet described in the PubMLST database. The cgMLST allocated the Brazilian
strains studied into five main clusters and each cluster comprised groups of strains with nearly identical cgMLST
profiles and with significant genetic distance observed among the distinct clusters. The comparison of the Brazilian
strains with 3401 isolates from different countries showed a wide distribution of these strains isolated in
this country.
Conclusions: The results showed a high similarity among some strains studied and a wide distribution of the
Brazilian strains when compared to isolates from different countries, which is an interesting data set since it
showed a high genetic diversity of these strains from Brazil in a global context. This study contributed for a better
genomic characterization of C. coli strains isolated in Brazil and provided important information about the diversity
of this clinically-relevant pathogen. 2024