Article

Boosting of cellular immunity against Mycobacterium tuberculosis and modulation of skin cytokine responses in healthy human volunteers by Mycobacterium bovis BCG substrain Moreau Rio de Janeiro oral vaccine

Registro en:
COSGROVE, Catherine A. et al. Boosting of Cellular Immunity against Mycobacterium tuberculosis and Modulation of Skin Cytokine Responses in Healthy Human Volunteers by Mycobacterium bovis BCG Substrain Moreau Rio de Janeiro Oral Vaccine. Infection and Immunity, v. 74, n. 4, p. 2449-2452, Apr. 2006.
0019-9567
10.1128/IAI.74.4.2449-2452.2006
1098-5522
Autor
Cosgrove, Catherine A.
Castello Branco, Luiz R. R.
Hussell, Tracy
Sexton, Amy
Giemza, Rafaela
Phillips, Richard
Williams, Andrew
Griffin, George E.
Dougan, Gordon
Lewis, David J. M.
Institución
Resumen
Oral immunization of healthy adults with 10(7) CFU BCG Moreau Rio de Janeiro was well tolerated and significantly boosted gamma interferon responses to purified protein derivative, Ag85, and MPB70 from previous childhood intradermal BCG immunization. Oral BCG offers the possibility of a needle-free tuberculosis vaccine and of boosting the protective immunity from intradermal tuberculosis vaccines.
 
2025-01-01
 
Materias
BCG

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