Article
Confirmed Invasive Pulmonary Aspergillosis and COVID-19: the value of postmortem findings to support antemortem management
Registro en:
SANTANA, Monique Freire et al. Confirmed Invasive Pulmonary Aspergillosis and COVID-19: the value of postmortem findings to support antemortem management. Revista da Sociedade Brasileira de Medicina Tropical, Uberaba, v. 53, p. 1-4, 2020.
0037-8682
10.1590/0037-8682-0401-2020
1678-9849
Autor
Santana, Monique Freire
Pivoto, Guilherme
Alexandre, Márcia A. Araujo
Silva, Djane Clarys Baía da
Borba, Mayla Gabriela da Silva
Val, Fernando Almeida
Sousa, Jose Diego Brito
Melo, Gisely Cardoso
Monteiro, Wuelton Marcelo
Souza, João Vicente Braga
Pinheiro, Silviane Bezerra
Ferreira, Luiz Carlos Lima
Naveca, Felipe Gomes
Nascimento, Valdinete Alves
Corado, André Lima Guerra
Hajjar, Ludhmila Abrahão
Silva Neto, João Ricardo
Siva, George Alan Villarouco
Pasqualotto, Alessandro C.
Lacerda, Marcus Vinícius Guimarães
Resumen
We present postmortem evidence of invasive pulmonary aspergillosis (IPA) in a patient with severe COVID-19. Autopsies of COVID-19 confirmed cases were performed. The patient died despite antimicrobials, mechanical ventilation, and vasopressor support. Histopathology and peripheral blood galactomannan antigen testing confirmed IPA. Aspergillus penicillioides infection was confirmed by nucleotide sequencing and BLAST analysis. Further reports are needed to assess the occurrence and frequency of IPA in SARS-CoV-2 infections, and how they interact clinically.