First report of treatment failure in a patient with cutaneous leishmaniasis infected by Leishmania (Viannia) naiffi carrying Leishmania RNA virus: a fortuitous combination?

dc.creatorVieira-Gonçalves, Ricardo
dc.creatorFagundes-Silva, Giselle Aparecida
dc.creatorHeringer, Júlia Furtado
dc.creatorFantinatti, Maria
dc.creatorCruz, Alda Maria da
dc.creatorOliveira-Neto, Manoel Paes
dc.creatorGuerra, Jorge Augusto Oliveira
dc.creatorGomes-Silva, Adriano
dc.date2019-06-03T13:56:15Z
dc.date2019-06-03T13:56:15Z
dc.date2019
dc.date.accessioned2023-09-27T00:12:04Z
dc.date.available2023-09-27T00:12:04Z
dc.identifierVIEIRA-GONÇALVES, Ricardo et al. First report of treatment failure in a patient with cutaneous leishmaniasis infected by Leishmania (Viannia) naiffi carrying Leishmania RNA virus: a fortuitous combination? Revista da Sociedade Brasileira de Medicina Tropical, v. 52, p. 1-3, 2019.
dc.identifier0037-8682
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/33321
dc.identifier10.1590/0037-8682-0323-2018
dc.identifier1678-9849
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8898457
dc.descriptionWe report the case of a 32-year-old man from Rio de Janeiro, who was infected in the Amazon region of Brazil by Leishmania (Viannia) naiffi. Generally, patients with L. naiffi cutaneous leishmaniasis exhibit a good therapeutic response to either pentavalent antimonials or pentamidine. However, after pentamidine treatment, this patient's infection evolved to therapeutic failure. To understand this clinical outcome, we investigated the presence of the Leishmania RNA virus (LRV) in parasites isolated from the cutaneous lesion; herein, we discuss the possible association between a poor response to pentamidine therapy and the presence of the LRV.
dc.formatapplication/pdf
dc.languageeng
dc.publisherSociedade Brasileira de Medicina Tropical
dc.rightsopen access
dc.subjectLeishmania (Viannia) naiff
dc.subjectTherapeutic failure
dc.subjectLeishmania RNA virus
dc.titleFirst report of treatment failure in a patient with cutaneous leishmaniasis infected by Leishmania (Viannia) naiffi carrying Leishmania RNA virus: a fortuitous combination?
dc.typeArticle


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