Mucormycosis in Mato Grosso, Brazil: a case reports, caused by Rhizopus microsporus var. oligosporus and Rhizopus microsporus var. rhizopodiformis

dc.creatorRibeiro, Luciano Corrêa
dc.creatorWanke, Bodo
dc.creatorSilva, Manuela da
dc.creatorDias, Luciana Basili
dc.creatorMello, Renato
dc.creatorCanavarros, Fernando Artur Pena Borges
dc.creatorLeite-Jr, Diniz Pereira
dc.creatorHahn, Rosane Christine
dc.date2019-10-22T13:02:26Z
dc.date2019-10-22T13:02:26Z
dc.date2012
dc.date.accessioned2023-09-27T00:10:22Z
dc.date.available2023-09-27T00:10:22Z
dc.identifierRIBEIRO, Luciano Corrêa et al. Mucormycosis in Mato Grosso, Brazil: a case reports, caused by Rhizopus microsporus var. oligosporus and Rhizopus microsporus var. rhizopodiformis. Mycopathologia, v. 173, p. 187-192, 2012.
dc.identifier0301-486X
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/36627
dc.identifier10.1007/s11046-011-9472-0
dc.identifier1573-0832
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8898165
dc.descriptionWe identified the etiological agents responsible for two fatal cases of rhinocerebral mucormycosis with the classical risk factor for uncontrolled type II diabetes mellitus. Their initial symptoms did not point immediately to the suspicion of mucormycosis. Case 1, caused by Rhizopus microsporus var. oligosporus, was a 52-year-old man who presented with a painful pimple on his nose, which evolved with swelling, erythema, and a central pustule on his right hemiface suspected to be cellulitis. After 7 days of antibiotic treatment, the patient worsened with signs of sepsis and the lesion evolved to necrosis involving all his right face. Case 2, caused by Rhizopus microsporus var. rhizopodiformis, was a 57-year-old woman placed on continuous therapy with azathioprine and corticoids after a renal transplant due to chronic arterial hypertension and uncontrolled type II diabetes mellitus. Because she was suspected to have sepsis, the patient was treated with broadspectrum antibiotics and mechanical ventilation, yet she deteriorated. Because Candida spp. were isolated from urine and a BAL, she was treated with fluconazole for 10 days, then substituted by caspofungin. Two weeks later, she presented with exophthalmus of the left eye that was surrounded by a large inflammatory and necrotic area. Both patients were the diagnosed with mucormycosis via direct microscopy of necrotic material prior to their death.
dc.description2020-10-22
dc.formatapplication/pdf
dc.languageeng
dc.publisherSpringer Verlag
dc.rightsopen access
dc.subjectMucormycosis
dc.subjectBrazil
dc.subjectRhizopus microsporus var. oligosporus
dc.subjectRhizopus microsporus var. rhizopodiformis
dc.titleMucormycosis in Mato Grosso, Brazil: a case reports, caused by Rhizopus microsporus var. oligosporus and Rhizopus microsporus var. rhizopodiformis
dc.typeArticle


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