Article
Evidence for a regulatory role of alpha 4-integrins in the maturation of eosinophils generated from the bone marrow in the presence of dexamethasone
Registro en:
GASPAR-ELSAS, M. I. et al. Evidence for a regulatory role of a4 – integrins in the maturation of eosinophils generated from the bone marrow in the presence of dexamethasone. Clinical & Experimental Allergy, v. 39, p. 1187-1198, 2009.
0954-7894
10.1111/j.1365-2222.2009.03289.x
1365-2222
Autor
Gaspar-Elsas, M. I.
Queto, T.
Vasconcelos, Zilton Farias Meira de
Jones, C. P.
Lannes-Vieira, Joseli
Xavier-Elsas, P.
Resumen
Although eosinophils co-express multiple integrin receptors, the contributions of integrins to eosinophil development have not been explored. We previously described extensive aggregation and cytological immaturity in eosinophils developing in bone-marrow (BM) cultures exposed to dexamethasone. Here we examined the relationship of alpha 4 integrins with these effects of dexamethasone. 2030-01-01