| dc.contributor | Universidade Estadual Paulista (UNESP) | |
| dc.creator | Bruschi, M. L. | |
| dc.creator | Lopes, R. S. | |
| dc.creator | Franco, S. L. | |
| dc.creator | Gremião, Maria Palmira Daflon | |
| dc.date | 2014-05-27T11:21:14Z | |
| dc.date | 2016-10-25T18:20:19Z | |
| dc.date | 2014-05-27T11:21:14Z | |
| dc.date | 2016-10-25T18:20:19Z | |
| dc.date | 2004-12-01 | |
| dc.date.accessioned | 2017-04-06T01:11:52Z | |
| dc.date.available | 2017-04-06T01:11:52Z | |
| dc.identifier | Revista de Ciencias Farmaceuticas, v. 25, n. 2, p. 79-84, 2004. | |
| dc.identifier | 0101-3793 | |
| dc.identifier | http://hdl.handle.net/11449/68067 | |
| dc.identifier | http://acervodigital.unesp.br/handle/11449/68067 | |
| dc.identifier | 2-s2.0-27444434566 | |
| dc.identifier.uri | http://repositorioslatinoamericanos.uchile.cl/handle/2250/889449 | |
| dc.description | The purpose of this study was to investigate the in vitro release of propolis from gelatin microparticles. Gelatin microparticles containing propolis extractive solution (PES) were prepared by spray-drying technique. Microparticles with a mean diameter of 2.50 μm and with regular morphology were obtained. The entrapment efficiency of propolis in the microparticles was over 39%. Spray-drying showed to be a feasible method for the preparation of gelatin microparticles containing propolis. Comparing to PES, the in vitro release of propolis from gelatin microparticles in aqueous medium was slower, considering markers 1 and 2. Thus, it was possible to transform a liquid propolis dosage form into a solid one, improving manipulation, packaging and storage and with modified release in aqueous medium, comparatively to the ethanolic extract of the drug. | |
| dc.language | eng | |
| dc.relation | Revista de Ciencias Farmaceuticas | |
| dc.rights | info:eu-repo/semantics/closedAccess | |
| dc.subject | Gelatin | |
| dc.subject | In vitro release | |
| dc.subject | Microencapsulation | |
| dc.subject | Microparticles | |
| dc.subject | Propolis | |
| dc.subject | Spray-drying | |
| dc.subject | gelatin | |
| dc.subject | nanoparticle | |
| dc.subject | propolis | |
| dc.subject | aqueous solution | |
| dc.subject | drug release | |
| dc.subject | feasibility study | |
| dc.subject | in vitro study | |
| dc.subject | morphology | |
| dc.subject | spray drying | |
| dc.subject | technique | |
| dc.title | In vitro release of propolis from gelatin microparticles prepared by spray-drying technique | |
| dc.type | Otro | |
