Choroidal vasculature in diabetic rats

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorRodrigues, Antonio Carlos Lottelli
dc.creatorSchellini, Silvana Artioli
dc.creatorGregório, E. A.
dc.creatorSpadella, César Tadeu
dc.creatorPadovani, Carlos Roberto
dc.date2014-05-27T11:21:07Z
dc.date2016-10-25T18:19:44Z
dc.date2014-05-27T11:21:07Z
dc.date2016-10-25T18:19:44Z
dc.date2004-07-01
dc.date.accessioned2017-04-06T01:09:45Z
dc.date.available2017-04-06T01:09:45Z
dc.identifierJournal of Submicroscopic Cytology and Pathology, v. 36, n. 3-4, p. 327-331, 2004.
dc.identifier1122-9497
dc.identifierhttp://hdl.handle.net/11449/67798
dc.identifierhttp://acervodigital.unesp.br/handle/11449/67798
dc.identifier2-s2.0-17444402041
dc.identifierhttp://www.ncbi.nlm.nih.gov/pubmed/15906609
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/889209
dc.descriptionThis study aims to evaluate the diabetic influence on the choroidal vessels morphology. Twenty Wistar rats were divided into a control (CG) and a diabetic group (DG). The animals had the diabetes induced by an intra-venous injection of Alloxan (42 mg/kg). Transmission electron microscopy analysis focusing the choroidal vessels was done one (T2) and twelve (T3) months after the diabetes induction. The CG rats in T3 showed vesicles and dense bodies in the endothelial and pericytic cells; the same structures were observed in the DG at T2. The DG rats in T3 had even more and intense changes than the T2DG rats. The morphological evaluation indicates that the choroidal vessels are affected in diabetes and the disease accelerates degenerative processes in the rat choroidal vasculature.
dc.languageeng
dc.relationJournal of Submicroscopic Cytology and Pathology
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectAloxan
dc.subjectChoriocapillary
dc.subjectChoroid
dc.subjectDiabetes
dc.subjectExperimental study
dc.subjectRats
dc.subjectalloxan
dc.subjectanimal experiment
dc.subjectanimal model
dc.subjectanimal tissue
dc.subjectchoroid
dc.subjectchoroid vascularization
dc.subjectcontrolled study
dc.subjectdiabetes mellitus
dc.subjectendothelium cell
dc.subjectfemale
dc.subjectmale
dc.subjectmorphology
dc.subjectnonhuman
dc.subjectpericyte
dc.subjectrat
dc.subjectrat strain
dc.subjecttransmission electron microscopy
dc.subjectAlloxan
dc.subjectAnimals
dc.subjectBasement Membrane
dc.subjectCapillaries
dc.subjectDiabetes Mellitus, Experimental
dc.subjectEndothelial Cells
dc.subjectFemale
dc.subjectMale
dc.subjectMicroscopy, Electron, Transmission
dc.subjectRats, Wistar
dc.subjectStromal Cells
dc.titleChoroidal vasculature in diabetic rats
dc.typeOtro


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