Flow cytometry as a tool to identify Mycobacterium tuberculosis interaction with the immune system and drug susceptibility

dc.creatorBonecini-Almeida, Maria da Gloria
dc.date2019-06-20T22:19:43Z
dc.date2019-06-20T22:19:43Z
dc.date2000
dc.date.accessioned2023-09-26T23:10:28Z
dc.date.available2023-09-26T23:10:28Z
dc.identifierBONECINI-ALMEIDA, Maria da Gloria et al. Flow cytometry as a tool to identify Mycobacterium tuberculosis interaction with the immune system and drug susceptibility. Memórias do Instituto Oswaldo Cruz. Rio de Janeiro, v. 95, v. 4, p. 491-494, 2000.
dc.identifier0074-0276
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/33610
dc.identifier10.1590/S0074-02762000000400008
dc.identifier1678-8060
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8887662
dc.descriptionFlow cytometric analysis is a useful and widely employed tool to identify immunological alterations caused by different microorganisms, including Mycobacterium tuberculosis. However, this tool can be used for several others analysis. We will discuss some applications for flow cytometry to the study of M. tuberculosis, mainly on cell surface antigens, mycobacterial secreted proteins, their interaction with the immune system using inflammatory cells recovered from peripheral blood, alveolar and pleura spaces and the influence of M. tuberculosis on apoptosis, and finally the rapid determination of drug susceptibility. All of these examples highlight the usefulness of flow cytometry in the study of M. tuberculosis infection.
dc.formatapplication/pdf
dc.languageeng
dc.publisherInstituto Oswaldo Cruz
dc.rightsopen access
dc.subjectTuberculosis
dc.subjectMacrophages
dc.subjectDrug susceptibility
dc.subjectCytometry
dc.titleFlow cytometry as a tool to identify Mycobacterium tuberculosis interaction with the immune system and drug susceptibility
dc.typeArticle


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