Atividade antiedema do pró-fármaco polimérico PDC-70 derivado do diclofenaco

Nassute, José Carlos; Longo, Maria do Carmo; Menegon, Renato Farina; Ribeiro, Yoko Asakura; Chin, Chung Man

Otro

Registro en:

Revista de Ciencias Farmaceuticas, v. 23, n. 2, p. 255-261, 2002.

0101-3793

http://hdl.handle.net/11449/67122

http://acervodigital.unesp.br/handle/11449/67122

2-s2.0-0042932293

http://repositorioslatinoamericanos.uchile.cl/handle/2250/888607

Autor

Nassute, José Carlos

Longo, Maria do Carmo

Menegon, Renato Farina

Ribeiro, Yoko Asakura

Chin, Chung Man

Institución

Universidade Paulista Júlio de Mesquita Filho (Brasil)

Resumen

The PDC-70 polymeric prodrug derived from the diclofenac has shown antiedema activity when administered through intramuscular route in rats. Besides that it has produced superior activity when compared to the diclofenac sodium. These promising results indicate antiinflammatory activity for the PDC-70 polymeric prodrug.