Myocardial infarction or myocarditis? a case report and review of a myocardial adverse event associated with mRNA vaccine

dc.creatorBadaró, Roberto
dc.creatorNovaes, Gustavo
dc.creatorAndrade, Ana Cristina
dc.creatorAraujo Neto, Cesar Augusto de
dc.creatorMachado, Bruna Aparecida
dc.creatorBarbosa, Josiane Dantas Viana
dc.creatorSoares, Milena Botelho Pereira
dc.date2023-06-06T18:31:13Z
dc.date2023-06-06T18:31:13Z
dc.date2023
dc.date.accessioned2023-09-26T22:55:10Z
dc.date.available2023-09-26T22:55:10Z
dc.identifierBADARÓ, Roberto et al. Myocardial infarction or myocarditis? a case report and review of a myocardial adverse event associated with mRNA vaccine. Frontiers in Medicine, v. 10, p. 1-6, 2023.
dc.identifier2296-858X
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/58957
dc.identifier10.3389/fmed.2023.1071239
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8884752
dc.descriptionInstituto SENAI de Inovação (ISI) em Sistemas Avançados de Saúde, Centro Universitário. Conselho Nacional do Brasil (CNPq).
dc.descriptionA 23-year-old man started with chest pain 8 h after his first Pfizer-BioNTech COVID 19 vaccination. ECG evaluation showed sinus tachycardia with ST-segment elevation in D1, AVL, V5, and V6, the findings compatible with acute subepicardial myocardial damage. However, cardiac MRI documented myocardial fibrosis, with cardiac late enhancement non-ischemic pattern with diffuse edema. He had no other symptoms to suggest another etiology than the vaccination. The patient was hospitalized and received corticosteroid (prednisolone) daily. Then, 2 weeks after hospitalization, all laboratory parameters and ECG were normal and the patient was discharged from the hospital. The patient had a history of Wolf-Parkinson White that was corrected with ablation when he was 11 years old. This report calls attention to myocardial adverse reaction risk for mRNA COVID-19 vaccines for people with a previous cardiac disease history.
dc.formatapplication/pdf
dc.languageeng
dc.publisherFrontiers Media
dc.rightsopen access
dc.subjectCOVID-19
dc.subjectVacina mRNA
dc.subjectCardiotoxicidade
dc.subjectDoença cardíaca
dc.subjectEvento adverso
dc.subjectCOVID-19
dc.subjectmRNA vaccine
dc.subjectCardiotoxicity
dc.subjectCardiac disease
dc.subjectAdverse event
dc.subjectCOVID-19
dc.subjectVacina de mRNA-1273 contra 2019-nCoV
dc.subjectCardiotoxicidade
dc.subjectDoenças Cardiovasculares
dc.titleMyocardial infarction or myocarditis? a case report and review of a myocardial adverse event associated with mRNA vaccine
dc.typeArticle


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