Diethylcarbamazine attenuates the expression of pro-fibrogenic markers and hepatic stellate cells activation in carbon tetrachloride-induced liver fibrosis

França, Maria Eduarda Rocha de; Rocha, Sura Wanessa Santos; Oliveira, Wilma Helena; Santos, Laise Aline; Oliveira, Anne Gabrielle Vasconcelos de; Barbosa, Karla Patrícia Sousa; Nunes, Ana Karolina Santana; Rodrigues, Gabriel Barros; Lós, Deniele Bezerra; Peixoto, Christina Alves

Article

Registro en:

FRANÇA, Maria Eduarda Rocha de et al. Diethylcarbamazine attenuates the expression of pro-fibrogenic markers and hepatic stellate cells activation in carbon tetrachloride-induced liver fibrosis. Inflammopharmacology, v. 26, n. 2, p. 599–609, abr. 2018.

0925-4692

https://www.arca.fiocruz.br/handle/icict/37294

10.1007/s10787-017-0329-0

1568-5608

https://repositorioslatinoamericanos.uchile.cl/handle/2250/8884277

Autor

França, Maria Eduarda Rocha de

Rocha, Sura Wanessa Santos

Oliveira, Wilma Helena

Santos, Laise Aline

Oliveira, Anne Gabrielle Vasconcelos de

Barbosa, Karla Patrícia Sousa

Nunes, Ana Karolina Santana

Rodrigues, Gabriel Barros

Lós, Deniele Bezerra

Peixoto, Christina Alves

Institución

Instituto de Comunicação e Informação Científica e Tecnológica em Saúde (Brasil)

Resumen

CAPES; UFPE; IAM / FIOCRUZ

While diethylcarbamazine citrate (DEC) displays important anti-inflammatory effects in experimental models of liver injury, the mechanisms of its action remain poorly understood. The aim of the present study was to investigate the fibrolytic potential of DEC.

2050-01-01