Article
Impact of depression on quality of life in people living with human T cell lymphotropic virus type 1 (HTLV-1) in Salvador, Brazil.
Registro en:
GALVÃO-CASTRO, A. V. et al. Impact of depression on quality of life in people living with human T cell lymphotropic virus type 1 (HTLV-1) in Salvador, Brazil. Quality of Life Research, v. 21, n. 9, p. 1545-1550, 2012.
1573-2649
10.1007/s11136-011-0066-6
Autor
Castro, Ana Verena Galvão
Boa-Sorte, Ney Cristian Amaral
Kruschewsky, Ramon de Almeida
Grassi, Maria Fernanda Rios
Castro Filho, Bernardo Galvão
Resumen
Purpose A previous study found the prevalence of
depression in HTLV-1-infected patients to be approximately
30%, but few studies have attempted to correlate
depression with quality of life (QOL) in these patients. The
present study investigates the association between depression
and QOL in people living with HTLV-1.
Methods A clinical-epidemiological questionnaire, the Mini
International Neuropsychiatric Interview and the WHOQOLBref
were applied to 88 HTLV-1-infected patients (32 with
TSP/HAM) at the HTLV Center of the Bahiana School of
Medicine and Public Health, Salvador, Brazil.
Results The prevalence of depression among people living
with HTLV-1 was 34.1%. Depression was significantly
associated with a poor QOL in the physical, psychological,
social relationship and environment domains, when controlling
for other variables, such as gender, age, time of
knowledge of serological diagnosis and presence of tropical
spastic paraparesis/HTLV-1associated myelopathy (TSP/
HAM). Moreover, patients with TSP/HAM experienced a
reduction in their QOL in the physical, psychological and
environment domains.
Conclusion Our results showed that depression negatively
affects the quality of life of people living with HTLV-1,
regardless of the presence of TSP/HAM. Since it is possible to
improve a patient’s QOL by treating depression, psychological
evaluations are strongly recommended as a measure to
integrate the treatment protocols of HTLV-1 intervention
programs.