Article
Chemoresistance of Plasmodium falciparum and Plasmodium vivax parasites in Brazil: consequences on disease morbidity and control
Registro en:
GAMA, Bianca E. et al. Chemoresistance of Plasmodium falciparum and Plasmodium vivax parasites in Brazil: consequences on disease morbidity and control. Mem Inst Oswaldo Cruz, v.106, Suppl. I, p.159-166, 2011.
0074-0276
1678-8060
Autor
Gama, Bianca Ervatti
Lacwrda, Marcus Vinicius Guimarães
Daniel-Ribeiro, Cláudio Tadeu
Cruz, Maria de Fátima Ferreira da
Resumen
In Brazil, malaria still remains a clinically important febrile syndrome for local populations and travelers, occurring mostly in the Amazon Basin. This review aims to report the main efforts employed to control this disease since the 1940s and the emergence of Plasmodium falciparum and Plasmodium vivax chemoresistance to chloroquine and sulphadoxine-pyrimethamine among other drugs. Additionally, in vivo, in vitro and molecular studies as well as malaria chemoresistance consequences on disease morbidity and policy treatment guidelines were commented.
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