Article
Molecular characterization of Candida spp. isolates from patients with bloodstream infections
Registro en:
XAVIER, Paula Cristhina Niz; et al. Molecular characterization of Candida spp. isolates from patients with bloodstream infections. Revista da Sociedade Brasileira de Medicina Tropical, v.46, n.6, p.786-787, Nov-Dec, 2013.
0037-8682
10.1590/0037-8682-1718-2013
Autor
Xavier, Paula Cristhina Niz
Chang, Marilene Rodrigues
Paula, Claudete Rodrigues
Matsumoto, Flávia Emi
Asensi, Marise Dutra
Matos, Maria de Fátima Cepa
Andreotti, Renato
Resumen
The aim of this study was to conduct an epidemiological study comparing the genetic similarity of yeasts isolated
from blood cultures. Methods: Random amplifi cation of polymorphic DNA (RAPD) techniques were used for the Candida
samples obtained from patients at the Hospital Universitário da Universidade Federal do Mato Grosso do Sul (HU/UFMS) in
Campo Grande, State of Mato Grosso do Sul, Brazil, from 1998-2000. Results: The most frequently isolated species was Candida
albicans (45.8%). DNA amplifi cation from genomic yeast isolates indicated a genetic similarity of over 90%. Conclusions: The
RAPD profi les obtained were able to differentiate between the isolated Candida species, thereby suggesting that the method might
be useful in epidemiological studies.