Carbapenemase-resistant enterobacteria that produce the blaNDM gene are found worldwide. However, this is the first report of blaNDM in Klebsiella aerogenes in Brazil. Methods: The identification of bacterial species was performed using anautomated system and confirmed by biochemical tests, 16S rRNA gene sequencing, and detection of resistance genes. Results: The clinical isolate showed minimum inhibitory concentration resistance to meropenem and polymyxin B at 8mg/L and 4mg/L, respectively. Only the blaNDM gene was detected. Conclusions: The current report of the bla NDM gene in isolated MDR enterobacteria indicates that this gene can spread silently in a hospital setting.