Article
Clinical conditions associated with intestinal strongyloidiasis in Rio de Janeiro, Brazil
Registro en:
CABRAL, Anna Caryna; et al. Clinical conditions associated withintestinal strongyloidiasis in Rio de Janeiro, Brazil. Rev. Soc. Bras. Med. Trop., v.48, n.3, p.321-325, May-June 2015.
1678-9849
10.1590/0037-8682-0019-2015
Autor
Cabral, Anna Caryna
Iñiguez, Alena Mayo
Moreno, Taiza
Bóia, Márcio Neves
Costa, Filipe Anibal Carvalho
Resumen
Introduction: Strongyloides stercoralis is a soil-transmitted helminth that produces an infection that can persist for decades.
The relationships between certain clinical conditions and strongyloidiasis remains controversial. This study aims to identify
the clinical conditions associated with intestinal strongyloidiasis at a reference center for infectious diseases in Rio de Janeiro,
Brazil. Methods: The clinical conditions that were assessed included HIV/AIDS, HTLV infection, cardiovascular diseases,
diabetes, obstructive respiratory diseases, viral hepatitis, tuberculosis, cancer, chronic renal disease, nutritional/metabolic
disorders, psychiatric conditions, rheumatic diseases and dermatologic diseases. We compared 167 S. stercoralis-positive
and 133 S. stercoralis-negative patients. Results: After controlling for sex (male/female OR = 2.29; 95% (CI): (1.42 - 3.70),
rheumatic diseases remained signifi cantly associated with intestinal strongyloidiasis (OR: 4.96; 95% CI: 1.34-18.37) in a
multiple logistic regression model. With respect to leukocyte counts, patients with strongyloidiasis presented with signifi cantly
higher relative eosinophil (10.32% ± 7.2 vs. 4.23% ± 2.92) and monocyte (8.49% ± 7.25 vs. 5.39% ± 4.31) counts and lower
segmented neutrophil (52.85% ± 15.31 vs. 61.32% ± 11.4) and lymphocyte counts (28.11% ± 9.72 vs. 30.90% ± 9.51) than
S. stercoralis-negative patients. Conclusions: Strongyloidiasis should be routinely investigated in hospitalized patients with
complex conditions facilitate the treatment of patients who will undergo immunosuppressive therapy. Diagnoses should be
determined through the use of appropriate parasitological methods, such as the Baermann-Moraes technique.