Article
ADCC-Mediated CD56DIM NK Cell Responses Are Associated with Early HBsAg Clearance in Acute HBV Infection
Registro en:
YOU, Wen-Han et al. ADCC-Mediated CD56DIM NK Cell Responses are Associated with early HBsAg Clearence in Acute HBV Infection. Pathogens and Immunity, v. 3, n. 1, p.1-2, Feb. 2018.
2469-2964
10.20411/pai.v3i1.228
Autor
Yu, Wen-Han
Cosgrove, Cormac
Berger, Christoph T.
Cheney, Patrick C.
Krykbaeva, Marina
Kim, Arthur Y.
Lewis-Ximenez, Lia
Lauer, Georg M.
Alter, Galit
Resumen
Hepatitis B virus (HBV) affects up to 400 million people worldwide and accounts for approximately one million deaths per year from liver pathologies. Current treatment regimens are effective in suppressing viremia but usually have to be taken indefinitely, warranting research into new therapeutic approaches. Acute HBV infection in adults almost universally results in resolution of viremia, with the exception of immunocompromised persons, suggesting that the immune response can functionally cure or even eradicate HBV infection.