E.F. Oliveira-Filho e R. Durães-Carvalho são apoiados pelas bolsas DCF do FACEPE e do DCR do MCT / CNPq. J.V.J. Silva Júnior é apoiado pela Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES). T.R.R. A Lopes é apoiada pelo Conselho Nacional de Desvolvimento Científico e Tecnológico (CNPq).Emerging and re-emerging viral infections transmitted by insect vectors (arthopode-borne viruses, arbovirus) are a serious threat to global public health. Among them, yellow fever (YFV), dengue (DENV), chikungunya (CHIKV) and Zika (ZIKV) viruses are particularly important in tropical and subtropical regions. Although vector control is one of the most used prophylactic measures against arboviruses, it often faces obstacles, such as vector diversity, uncontrolled urbanization and increasing resistance to insecticides. In this context, vaccines may be the best control strategy for arboviral diseases. Here, we provide a general overview about licensed vaccines and the most advanced vaccine candidates against YFV, DENV, CHIKV and ZIKV. In particular, we highlight vaccine difficulties, the current status of the most advanced strategies and discuss how the molecular characteristics of each virus can influence the choice of the different vaccine formulations.2050-01-01