Challenges and perspectives in vaccination against leishmaniasis.

dc.creatorOliveira, Camila Indiani de
dc.creatorNascimento, Ivan Pereira
dc.creatorBarral, Aldina Maria Prado
dc.creatorSoto, Manuel
dc.creatorBarral Netto, Manoel
dc.date2014-03-13T13:32:09Z
dc.date2014-03-13T13:32:09Z
dc.date2009
dc.date.accessioned2023-09-26T22:17:08Z
dc.date.available2023-09-26T22:17:08Z
dc.identifierOLIVEIRA, C. I. de et al. Challenges and perspectives in vaccination against leishmaniasis. Parasitology International, v. 58, p. 319–324, 2009.
dc.identifier1873-0329
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/7401
dc.identifier10.1016/j.parint.2009.07.013
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8877314
dc.descriptionThe leishmaniases are a group of diseases caused by protozoa of the genus Leishmania and affect millions of people worldwide. The leishmaniases are transmitted to vertebrate hosts by phlebotomine sand flies. In this review, we focus on several issues that have been poorly addressed in ongoing efforts to develop a vaccine against Leishmania, namely: vaccination with antigens present in sand fly saliva, vaccines based on intracellular Leishmania antigens, and use of recombinant BCG as a vehicle for vaccination. Additionally, we address the differences between L. major and L. braziliensis and the impact that these differences may have on strategies for immunoprophylaxis
dc.formatapplication/pdf
dc.languageeng
dc.publisherElsevier Ireland Ltd.
dc.rightsopen access
dc.subjectLeishmania
dc.subjectSandy fly
dc.subjectSaliva
dc.subjectBCG
dc.subjectLeishmania braziliensis/imunologia
dc.subjectLeishmania major/imunologia
dc.subjectLeishmaniose Cutânea/prevenção & controle
dc.subjectVacinas Protozoárias
dc.subjectPsychodidae
dc.subjectSaliva
dc.subjectAnimais
dc.subjectAntígenos de Protozoários/genética
dc.subjectAntígenos de Protozoários/imunologia
dc.subjectAnimais
dc.subjectLeishmaniose Cutânea/parasitologia
dc.subjectCamundongos
dc.subjectMycobacterium bovis/genética
dc.subjectVacinas Protozoárias/administração & dosagem
dc.subjectVacinas Protozoárias/imunologia
dc.subjectPsychodidae/imunologia
dc.subjectPsychodidae/parasitologia
dc.subjectSaliva/imunologia
dc.subjectSaliva/parasitologia
dc.subjectVacinação
dc.titleChallenges and perspectives in vaccination against leishmaniasis.
dc.typeArticle


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