Article
In vitro analyses of the effect of aromatic diamidines upon Trypanosoma cruzi
Registro en:
DALIRY, Anissa et al. In vitro analyses of the effect of aromatic diamidines upon Trypanosoma cruzi. Journal of Antimicrobial Chemotherapy, v. 64, p. 747–750, 2009.
0305-7453
10.1093/jac/dkp290
1460-2091
Autor
Daliry, Anissa
Silva, Patrícia B. da
Silva, Cristiane F. da
Batista, Marcos Meuser
Castro, Solange L. de
Tidwell, Richard R.
Soeiro, Maria de Nazaré C.
Resumen
Aromatic diamidines (ADs) have been recognized as promising antiparasitic agents. Therefore, in the present work, the in vitro trypanocidal effect of 11 ADs upon the relevant clinical forms of Trypanosoma cruzi was evaluated, as well as determining their toxicity to mammalian cells and their subcellular localization. 2030-01-01