Maternal herpes-simplex infection at or near the time of delivery has frequently been suggested as the source of infection of the newborn. However, cases of infection in the first or second trimester of pregnancy are rarely related, as well as the examination of the placenta. In the second trimester of pregnancy an herpes-simplex maternal infections was considered as cause of abortion, by the typical placentary and fetal lesions, allied to the maternal clinical history. The histopathologic examination of the placenta in valuable as an aid in the diagnosis of certain fetal virus infections, mainly by the presence of cellular inclusions.