E-cadherin regulators are differentially expressed in the epithelium and stroma of keratocystic odontogenic tumors

dc.creatorPorto, Lia Pontes Arruda
dc.creatorSantos, Jean Nunes dos
dc.creatorRamalho, Luciana Maria Pedreira
dc.creatorFigueiredo, Andreia Leal
dc.creatorCarneiro Júnior, Bráulio
dc.creatorGurgel, Clarissa Araújo
dc.creatorPaiva, Katiúcia Batista Silva
dc.creatorXavier, Flávia Caló Aquino
dc.date2018-03-27T17:25:16Z
dc.date2018-03-27T17:25:16Z
dc.date2016
dc.date.accessioned2023-09-26T21:06:20Z
dc.date.available2023-09-26T21:06:20Z
dc.identifierPORTO, L. P. A. et al. E-cadherin regulators are differentially expressed in the epithelium and stroma of keratocystic odontogenic tumors. Journal of Oral Pathology & Medicine, v. 45, p. 302–311, 2016.
dc.identifier0904-2512
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/25532
dc.identifier10.1111/jop.12382
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8869226
dc.descriptionGurgel, Clarissa Araújo. “Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta à informação no documento”.
dc.descriptionThe epithelial-mesenchymal transition (EMT) is the process where cells lose their epithelial features and acquire properties of typical mesenchymal cells. The dissociation of tumor cells due to changes in cell-cell adhesion is one of the key principles of tumor invasion and EMT. Thus, the knowledge of the molecular features of EMT in keratocyst odontogenic tumor (KOT) can provide useful markers to aid in the diagnosis and prognosis and perhaps contribute to an alternative therapeutic approach as it shows an aggressive clinical behavior and high recurrence rates. This study aimed to evaluate the EMT in KOT by the immunoexpression of E-cadherin, N-cadherin, Snail, and Slug and comparing to radicular cysts and dental follicles.
dc.formatapplication/pdf
dc.languageeng
dc.publisherWiley
dc.rightsopen access
dc.subjectAdesão celular
dc.subjectE-caderina
dc.subjectTransição epitelial-mesenquimal
dc.subjectImuno-histoquímica
dc.subjectTumores odontogênicos
dc.subjectCell adhesion
dc.subjectE-cadherin
dc.subjectEpithelial–mesenchymal transition
dc.subjectImmunohistochemistry
dc.subjectOdontogenic tumors
dc.titleE-cadherin regulators are differentially expressed in the epithelium and stroma of keratocystic odontogenic tumors
dc.typeArticle


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