Article
Study of hantavirus infection in captive breed colonies of wild rodents
Registro en:
OLIVEIRA, R. C. et al. Study of hantavirus infection in captive breed colonies of wild rodents. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 99, n. 6, p. 575-576, Oct. 2004.
0074-0276
10.1590/S0074-02762004000600007
1678-8060
Autor
Oliveira, R. C.
Rozental, T.
Corrêa, A. A. Alves
D`Andrea, P. S.
Schatzmayr, H.
Cerqueira, R.
Lemos, Elba Regina S.
Resumen
Wild sigmondontine rodents are known to be the reservoir of several serotypes of New World hantaviruses. The
mechanism of viral transmission is by aerosol inhalation of the excreta from infected rodents. Considering that the
captive breed colonies of various wild mammals may present a potencial risk for hantaviral transmission, we
examined 85 speciemens of Thrichomys spp. (Echimyidae) and 17 speciemens of Nectomys squamipes
(Sigmodontinae) from our colony for the presence of hantavirus infections. Blood samples were assayed for the
presence of antibodies to Andes nucleocapsid antigen using enzyme-linked immunosorbent assay (ELISA). Additionally, serum samples from workers previously exposed to wild rodents, in the laboratories where the study was
conducted, were also tested by ELISA to investigate prevalence of anti-hantavirus IgG antibodies. All blood samples
were negative for hantavirus antibodies. Although these results suggest that those rodent’s colonies are hantavirus
free, the work emphasizes the need for hantavirus serological monitoring in wild colonized rodents and secure
handling potentially infected rodents as important biosafety measures.
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