Article

Intraurethral injection with LPS: an effective experimental model of prostatic inflammation

Registro en:
GOMES, Fabiana Oliveira dos Santos et al. Intraurethral Injection with LPS: An Effective Experimental Model of Prostatic Inflammation. Inflammation Research: Official Journal of the European Histamine Research Society, v. 67, n. 1, p. 43–55, Jan. 2018.
1420-908X
10.1007/s00011-017-1094-7
Autor
Gomes, Fabiana Oliveira dos Santos
Oliveira, Amanda Costa
Ribeiro, Edlene Lima
Silva, Bruna Santos da
Santos, Laise Aline Martins dos
Lima, Ingrid Tavares de
Silva, Amanda Karolina Soares E.
Araújo, Shyrlene Meiry da Rocha
Gonçalves, Terezinha
Melo-Junior, Mario Ribeiro de
Peixoto, Christina Alves
Institución
Resumen
Fundação Oswaldo Cruz. O CAP é apoiado por bolsas de pesquisa do Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq).
 
Chronic inflammation has been recognized as having a prominent role pathogenesis of benign prostatic hyperplasia (BPH) and cancer. It is believed that chronic inflammation induces prostatic fibromuscular growth. This correlation has been clearly illustrated by both in vivo and in vitro studies; however, current experimental models of BPH require complex surgery or hormonal treatment. Therefore, the aim of the present study was to propose a new murine model of BPH/prostatitis induced by intraurethral injection of LPS.
 
2050-01-01
 
Materias

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