Article
Strategies to Prevent Cholera Introduction during International Personnel Deployments: A Computational Modeling Analysis Based on the 2010 Haiti Outbreak
Registro en:
LEWNARD, J. A. et al. Strategies to Prevent Cholera Introduction during International Personnel Deployments: A Computational Modeling Analysis Based on the 2010 Haiti Outbreak. Plos Medicine, v. 13, n. 1, p. e1001947, 2016.
1549-1277
10.1371/journal.pmed.1001947
Autor
Lewnard, Joseph A
Antillón, Marina
Gonsalves, Gregg
Miller, Alice Maria
Ko, Albert Icksang
Pitzer, Virginia E
Resumen
Bill and Melinda Gates Foundation (OPP1091919) and the US National Institutes of Health (R01-AI112970, R01-TW009504, R01-AI052473). Introduction of Vibrio cholerae to Haiti during the deployment of United Nations (UN) peacekeepers in 2010 resulted in one of the largest cholera epidemics of the modern era. Following the outbreak, a UN-commissioned independent panel recommended three pre-deployment intervention strategies to minimize the risk of cholera introduction in future peacekeeping operations: screening for V. cholerae carriage, administering prophylactic antimicrobial chemotherapies, or immunizing with oral cholera vaccines. However, uncertainty regarding the effectiveness of these approaches has forestalled their implementation by the UN. We assessed how the interventions would have impacted the likelihood of the Haiti cholera epidemic.