Article
Mitochondria push platelets past their prime
Registro en:
BOZZA, Fernando A.; WEYRICH, Andrew S. Mitochondria push platelets past their prime. Blood, Philadelphia, v. 111, n. 5, p. 2496-2497, Mar. 2008.
0006-4971
10.1182/blood-2007-12-126193
1528-0020
Autor
Bozza, Fernando A.
Weyrich, Andrew S.
Resumen
In the February 1 issue of Blood, Jobe and colleagues elucidated the function of the mitochondrial permeability transition pore (MPTP), in platelet activation and demonstrated that cyclophilin D (CypD), a regulator of MPTP formation, is a critical factor in the procoagulant response to strong agonists.