Mitochondria push platelets past their prime

Bozza, Fernando A.; Weyrich, Andrew S.

Article

Registro en:

BOZZA, Fernando A.; WEYRICH, Andrew S. Mitochondria push platelets past their prime. Blood, Philadelphia, v. 111, n. 5, p. 2496-2497, Mar. 2008.

0006-4971

https://www.arca.fiocruz.br/handle/icict/57570

10.1182/blood-2007-12-126193

1528-0020

https://repositorioslatinoamericanos.uchile.cl/handle/2250/8865456

Autor

Bozza, Fernando A.

Weyrich, Andrew S.

Institución

Instituto de Comunicação e Informação Científica e Tecnológica em Saúde (Brasil)

Resumen

In the February 1 issue of Blood, Jobe and colleagues elucidated the function of the mitochondrial permeability transition pore (MPTP), in platelet activation and demonstrated that cyclophilin D (CypD), a regulator of MPTP formation, is a critical factor in the procoagulant response to strong agonists.

Materias

Mitochondria

Mitochondrial Permeability Transition Pore (MPTP)

Demonstrated that Cyclophilin D (CypD)

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