dc.creatorGoldsztajn, Karen O.
dc.creatorTrope, Beatriz Moritz
dc.creatorLenzi, Maria Elisa Ribeiro
dc.creatorCuzzi, Tullia
dc.creatorRamos-e-Silva, Marcia
dc.date2019-09-20T13:06:38Z
dc.date2019-09-20T13:06:38Z
dc.date2012
dc.date.accessioned2023-09-26T20:50:42Z
dc.date.available2023-09-26T20:50:42Z
dc.identifierGOLDSZTAJN, Karen O. et al. Granulomatous slack skin: histopathology diagnosis preceding clinical manifestations by 12 years. Journal of dermatological case reports, v. 4, p. 108-112, 2012.
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/35710
dc.identifier1898-7249
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8864892
dc.descriptionTullia Cuzzi. Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Documento produzido em parceria ou por autor vinculado à Fiocruz, mas não consta a informação no documento.
dc.descriptionBackground: Granulomatous slack skin is a very rare subtype of T-cell cutaneous lymphoma, characterized by the slow development of cutaneous sagging, especially on flexural areas. Its behavior is indolent and the treatment, in the majority of cases, disappointing. Main observations: We report a 54-year-old black patient with granulomatous slack skin, who at the beginning of the investigation showed intense xeroderma and generalized lymph node enlargement. The diagnosis was established based on histopathologic findings long before the disease’s characteristic clinical presentation appeared. Conclusion: During the twelve years of follow-up, the clinical manifestation evolved to marked skin looseness, most predominant in flexural regions, illustrating the clinical hallmark of granulomatous slack skin, long after first histological abnormalities were observed.
dc.formatapplication/pdf
dc.languageeng
dc.rightsopen access
dc.subjectCutaneous T-cell lymphoma
dc.subjectDiagnosis
dc.subjectGranulomatous cutis laxa
dc.subjectGranulomatous slack skin
dc.subjectLymphoma
dc.subjectMycosis fungoides
dc.subjectOrcein staining
dc.subjectTreatment
dc.titleGranulomatous slack skin: histopathology diagnosis preceding clinical manifestations by 12 years
dc.typeArticle


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