The Association of the Fat Mass and Obesity-Associated Gene (FTO) rs9939609 Polymorphism and the Severe Obesity in a Brazilian Population

dc.creatorFonseca, Ana Carolina Proença da
dc.creatorAbreu, Gabriella de Medeiros
dc.creatorZembrzuski, Veronica Marques
dc.creatorCampos Junior, Mario
dc.creatorCarneiro, João Regis Ivar
dc.creatorNogueira Neto, José Firmino
dc.creatorCabello, Giselda Maria Kalil
dc.creatorCabello, Pedro Hernán
dc.date2020-07-02T19:12:11Z
dc.date2020-07-02T19:12:11Z
dc.date2019
dc.date.accessioned2023-09-26T20:47:49Z
dc.date.available2023-09-26T20:47:49Z
dc.identifierFONSECA, Ana Carolina Proença da et al. The association of the fat mass and obesity-associated gene (FTO) rs9939609 polymorphism and the severe obesity in a Brazilian population. Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy, v. 12, p. 667-684, 2019.
dc.identifier1178-7007
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/42048
dc.identifier10.2147/DMSO.S199542. eCollection 2019
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8864061
dc.descriptionObesity occurs due to the interaction between the genetic background and environmental factors, including an increased food intake and a sedentary lifestyle. Nowadays, it is clear that there is a specific circuit, called leptin-melanocortin pathway, which stimulates and suppresses food intake and energy expenditure. Therefore, the aim of this study was to evaluate the influence of genetic variants related to appetite regulation and energy expenditure on severe obesity susceptibility and metabolic phenotypes in a Brazilian cohort.
dc.formatapplication/pdf
dc.languageeng
dc.publisherDove Medical Press
dc.rightsopen access
dc.subjectCaminho leptina-melanocortina
dc.subjectObesidade
dc.subjectPolimorfismos
dc.subjectHipotálamo
dc.subjectLeptin-melanocortin pathway
dc.subjectFTO
dc.subjectObesity
dc.subjectPolymorphisms
dc.subjectHypothalamus
dc.titleThe Association of the Fat Mass and Obesity-Associated Gene (FTO) rs9939609 Polymorphism and the Severe Obesity in a Brazilian Population
dc.typeArticle


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