Article
Clonal multidrug-resistant Corynebacterium striatum within a nosocomial environment, Rio de Janeiro, Brazil
Registro en:
BAIO, P. V. P. et al. Clonal multidrug-resistant Corynebacterium striatum within a nosocomial environment, Rio de Janeiro, Brazil. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 108, n. 1, p. 23-29, fev. 2013.
0074-0276
Autor
Baio, Paulo Victor Pereira
Mota, Higor Franceschi
Freitas, Andréa D'avila
Gomes, Débora Leandro Rama
Ramos, Juliana Nunes
Sant'Anna, Lincoln Oliveira
Souza, Mônica Cristina
Camello, Thereza Cristina Ferreira
Hirata Junior, Raphael
Vieira, Verônica Viana
Guaraldi, Ana Luíza Mattos
Resumen
Corynebacterium striatum is a potentially pathogenic microorganism with the ability to produce outbreaks of nosocomial infections. Here, we document a nosocomial outbreak caused by multidrug-resistant (MDR) C. striatum in Rio de Janeiro, Brazil. C. striatum identification was confirmed by 16S rRNA and rpoB gene sequencing. Fifteen C. striatum strains were isolated from adults (half of whom were 50 years of age and older). C. striatum was mostly isolated in pure culture from tracheal aspirates of patients undergoing endotracheal intubation procedures. The analysis by pulsed-field gel electrophoresis (PFGE) indicated the presence of four PFGE profiles, including two related clones of MDR strains (PFGE I and II). The data demonstrated the predominance of PFGE type I, comprising 11 MDR isolates that were mostly isolated from intensive care units and surgical wards. A potential causal link between death and MDR C. striatum (PFGE types I and II) infection was observed in five cases.