Article
Evaluation of the EIE-IgM-Leptospirose assay for the serodiagnosis of leptospirosis.
Registro en:
McBRIDE, A. j. A. et al. Evaluation of the EIE-IgM-Leptospirose assay for the serodiagnosis of leptospirosis. Acta Tropica, v. 102, n. 3, p. 206-211, 2007.
0001-706X
Autor
McBride, Alan John Alexander
Pereira, Fernanda Albuquerque
Silva, Emilson Domingos da
Matos, Rosan B. de
Silva, Edimilson Domingos da
Ferreira, Antonio Gomes Pinto
Reis, Mitermayer Galvão dos
Ko, Albert Icksang
Resumen
Access to low-cost, effective diagnosis for leptospirosis is urgently needed in developing countries. The EIE-IgM-Leptospirose, a kit produced for public health laboratories in Brazil, was shown to have a sensitivity of 76% (77 of 102 patients) and 100% (102 of 102 patients) during acute and convalescent-phase leptospirosis, respectively, and a specificity of 93-100% (total healthy and patient control subjects evaluated, 486). These findings indicate that the assay will be useful for diagnosis of this emerging infectious disease in Brazil and other developing countries.