ANALISE FAMILIAL DO COMPORTAMENTO IN VITRO DOS MACROFAGOS HUMANOS FRENTE AO MYCOBACTERIUM LEPRAE

dc.contributorUniversidade Estadual Paulista (UNESP)
dc.creatorFreire-Malia, D. V.
dc.date2014-05-26T21:07:11Z
dc.date2016-10-25T18:11:44Z
dc.date2014-05-26T21:07:11Z
dc.date2016-10-25T18:11:44Z
dc.date1983-12-01
dc.date.accessioned2017-04-06T00:39:45Z
dc.date.available2017-04-06T00:39:45Z
dc.identifierHansenologia Internationalis, v. 8, n. 2, p. 91-100, 1983.
dc.identifier0100-3283
dc.identifierhttp://hdl.handle.net/11449/63618
dc.identifierhttp://acervodigital.unesp.br/handle/11449/63618
dc.identifier2-s2.0-0020891125
dc.identifierhttp://www.ncbi.nlm.nih.gov/pubmed/6381302
dc.identifier.urihttp://repositorioslatinoamericanos.uchile.cl/handle/2250/885604
dc.descriptionThe lysogenic capacity of human macrophages facing M. leprae in vitro may be dependent on an important genetic component. Although the familial aggregation of the trait is demonstrated, this is a necessary but not sufficient condition to prove genetic influence. The data do not fit some simple genetic models (autosomal dominant or incompletely dominant gene; dominant or recessive sex-linked gene). The results obtained are consistent with the hypothesis that the macrophages' lysogenic capacity is mainly due to a major gene with variable expressivity. This hypothesis may be too simple to account for the whole variability detected and therefore must be considered a working hypothesis.
dc.languagepor
dc.relationHansenologia Internationalis
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectgenetics
dc.subjectheredity
dc.subjecthuman
dc.subjectleprosy
dc.subjectmacrophage
dc.subjectmycobacterium leprae
dc.subjectblood
dc.subjectin vitro study
dc.subjectMycobacterium leprae
dc.subjectphenotype
dc.subjectphysiology
dc.subjectEnglish Abstract
dc.subjectHuman
dc.subjectIn Vitro
dc.subjectLeprosy
dc.subjectMacrophages
dc.subjectPhenotype
dc.subjectSupport, Non-U.S. Gov't
dc.titleANALISE FAMILIAL DO COMPORTAMENTO IN VITRO DOS MACROFAGOS HUMANOS FRENTE AO MYCOBACTERIUM LEPRAE
dc.typeOtro


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