First report of Leishmania RNA virus 1 in Leishmania (Viannia) braziliensis clinical isolates from Rio de Janeiro State - Brazil

dc.creatorZabala-Peñafiel, Anabel
dc.creatorFantinatti, Maria
dc.creatorLopes, Geovane Dias
dc.creatorSilva, Jéssica Leite da
dc.creatorMiranda, Luciana de Freitas Campos
dc.creatorLyra, Marcelo Rosandiski
dc.creatorPimentel, Maria Inês Fernandes
dc.creatorSilva, Fátima Conceição
dc.creatorAlves, Carlos Roberto
dc.date2022-11-02T17:28:03Z
dc.date2022-11-02T17:28:03Z
dc.date2022
dc.date.accessioned2023-09-26T20:18:50Z
dc.date.available2023-09-26T20:18:50Z
dc.identifierZABALA-PENAFIEL, Anabel et al. First report of Leishmania RNA virus 1 in Leishmania (Viannia) braziliensis clinical isolates from Rio de Janeiro State - Brazil. Memórias do Instituto Oswaldo Cruz, Rio de Janeiro, v. 117, e210107, p. 1 - 6, July 2022.
dc.identifier0074-0206
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/55440
dc.identifier10.1590/0074-02760210107
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8853994
dc.descriptionBACKGROUND Leishmania parasites carry a double-stranded RNA virus (Leishmania RNA virus - LRV) that has been divided in LRV1 and LRV2. OBJECTIVES Leishmania (Viannia) braziliensis clinical isolates were assessed in order to determine LRV presence. METHODS Two-round polymerase chain reaction (PCR and nested PCR) was performed to detect LRV1 or LRV2 in L. (V.) braziliensis clinical isolates (n = 12). FINDINGS LRV1 was detected in three clinical isolates which was phylogenetically related to other sequences reported from other American tegumentary leishmaniasis (ATL) endemic areas of Brazil. Patients infected with L. (V.) braziliensis LRVnegative showed only cutaneous lesions while LRV-positive reported different manifestations. MAIN CONCLUSION Data presented here show for the first time that LRV1 is circulating in L. (V.) braziliensis clinical isolates from Rio de Janeiro State in Brazil.
dc.formatapplication/pdf
dc.languageeng
dc.publisherFundação Oswaldo Cruz. Instituto Oswaldo Cruz.
dc.rightsopen access
dc.subjectVírus RNA de Leishmania 1
dc.subjectLeishmania (Viannia) braziliensis
dc.subjectIsolados clínicos
dc.subjectRio de Janeiro
dc.subjectLeishmania RNA Virus 1
dc.subjectRio de Janeiro
dc.subjectLeishmania (Viannia) braziliensis
dc.subjectClinical isolates
dc.titleFirst report of Leishmania RNA virus 1 in Leishmania (Viannia) braziliensis clinical isolates from Rio de Janeiro State - Brazil
dc.typeArticle


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