Joint production of IL-22 participates in the initial phase of antigen-induced arthritis through IL-1β production

dc.creatorPinto, Larissa G.
dc.creatorTalbot, Jhimmy
dc.creatorPeres, Raphael S.
dc.creatorFranca, Rafael F.
dc.creatorFerreira, Sérgio H.
dc.creatorRyffel, Bernhard
dc.creatorAves-Filho, José Carlos F.
dc.creatorFigueiredo, Florêncio
dc.creatorCunha, Thiago M.
dc.creatorCunha, Fernando Q.
dc.date2017-09-20T19:38:49Z
dc.date2017-09-20T19:38:49Z
dc.date2015
dc.date.accessioned2023-09-26T20:17:58Z
dc.date.available2023-09-26T20:17:58Z
dc.identifierPINTO, L. G. et al. Joint production of IL-22 participates in the initial phase of antigen-induced arthritis through IL-1β production. Arthritis Research & Therapy, v. 17, p. 235, 2 set. 2015.
dc.identifier1478-6362
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/21078
dc.identifier10.1186/s13075-015-0759-2
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8853652
dc.descriptionRheumatoid arthritis (RA) is a chronic autoimmune disease characterized by neutrophil articular infiltration, joint pain and the progressive destruction of cartilage and bone. IL-22 is a key effector molecule that plays a critical role in autoimmune diseases. However, the function of IL-22 in the pathogenesis of RA remains controversial. In this study, we investigated the role of IL-22 in the early phase of antigen-induced arthritis (AIA) in mice.
dc.formatapplication/pdf
dc.languagepor
dc.rightsopen access
dc.subjectArtrite Experimental
dc.subjectInterleucina-1beta
dc.subjectInterleucinas
dc.subjectArticulação do Joelho
dc.subjectAnimals
dc.subjectAntigens
dc.subjectApoptosis Regulatory Proteins
dc.subjectArthralgia
dc.subjectArthritis, Experimental
dc.subjectCell Movement
dc.subjectEnzyme-Linked Immunosorbent Assay
dc.subjectEnzyme-Linked Immunosorbent Assay
dc.subjectGene Expression
dc.subjectInterleukin-1beta
dc.subjectKnee Joint
dc.subjectMice, Inbred C57BL
dc.subjectMice, Knockout
dc.subjectNeutrophils
dc.subjectReverse Transcriptase Polymerase Chain Reaction
dc.subjectSynovial Membrane
dc.subjectSynovitis
dc.subjectZymosan
dc.subjectArtrite Experimental
dc.subjectgenética
dc.subjectmetabolismo
dc.subjectimunologia
dc.subjectInterleucina-1beta
dc.subjectInterleucinas
dc.subjectAnimais
dc.subjectAntígenos
dc.subjectProteínas Reguladoras de Apoptose
dc.subjectArthralgia
dc.subjectMovimento Celular
dc.subjectEnsaio de Imunoadsorção Enzimática
dc.subjectExpressão Gênica
dc.subjectArticulação do Joelho
dc.subjectCamundongos Endogâmicos C57BL
dc.subjectCamundongos Knockout
dc.subjectNeutrófilos
dc.subjectReação em Cadeia da Polimerase Via Transcriptase Reversa
dc.subjectMembrana Sinovial
dc.subjectSinovite
dc.subjectZimosan
dc.titleJoint production of IL-22 participates in the initial phase of antigen-induced arthritis through IL-1β production
dc.typeArticle


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