Patients with COVID-19 and neurological manifestations show undetectable SARS-CoV-2 RNA levels in the cerebrospinal fluid

dc.creatorEspíndola, Otávio de Melo
dc.creatorSiqueira, Marilda Agudo Mendonça Teixeira de
dc.creatorSoares, Cristiane Nascimento
dc.creatorLima, Marco Antonio Sales Dantas de
dc.creatorLeite, Ana Claudia Celestino Bezerra
dc.creatorAraujo, Abelardo Queiroz Campos
dc.creatorBrandão, Carlos Otávio
dc.creatorSilva, Marcus Tulius Teixeira
dc.date2020-06-09T22:26:24Z
dc.date2020-06-09T22:26:24Z
dc.date2020
dc.date.accessioned2023-09-26T20:17:19Z
dc.date.available2023-09-26T20:17:19Z
dc.identifierESPÍNDOLA, Otávio de Melo et al. Patients with COVID-19 and neurological manifestations show undetectable SARS-CoV-2 RNA levels in the cerebrospinal fluid. International Journal of Infectious Diseases, v. 96, p. 567-569, 2020.
dc.identifier1201-9712
dc.identifierhttps://www.arca.fiocruz.br/handle/icict/41597
dc.identifier10.1016/j.ijid.2020.05.123
dc.identifier.urihttps://repositorioslatinoamericanos.uchile.cl/handle/2250/8853394
dc.descriptionA Rede Genômica Fiocruz é formada por especialistas de todas as unidades da Fundação no país e de institutos parceiros que se empenham diariamente em gerar dados mais robustos sobre o comportamento do SARS-Cov-2 e contribuir para um melhor preparo do país no enfrentamento da pandemia em termos de diagnóstico mais precisos e vacinas eficazes. Saiba mais sobre a Rede Genômica Fiocruz em: http://www.genomahcov.fiocruz.br/
dc.descriptionWe report that patients with COVID-19 displaying distinct neurological disorders have undetectable or extremely low levels of SARS-CoV-2 RNA in the cerebrospinal fluid, indicating that viral clearance precede the neurological involvement. This finding points to the need for the development of more sensitive molecular tests and the investigation of other neurotropic pathogens to exclude concurrent neuroinfection.
dc.formatapplication/pdf
dc.formatapplication/pdf
dc.languageeng
dc.publisherElsevier
dc.rightsopen access
dc.subjectRede Genômica Fiocruz
dc.subjectGENOMAHCOV
dc.subjectCOVID-19
dc.subjectSARS-CoV-2 RNA
dc.subjectRT-PCR
dc.subjectNeurological manifestations
dc.subjectCerebrospinal fluid
dc.titlePatients with COVID-19 and neurological manifestations show undetectable SARS-CoV-2 RNA levels in the cerebrospinal fluid
dc.typeArticle


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