Abstract: An 8-year-old boy was seen with a cutaneous Ki-1 anaplastic, large cell lymphoma with multiple lesions. Some of the lesions showed spontaneous regression. During more than seven years of disease no systemic involvement was observed, but recurrent, self-heal~ngle sions did appear. Histopathologic examination of five lesions revealed a variety of findings, from an inflammatory infiltrate to a highly anaplastic pattern. The neoplastic cells expressed Ki-1 and leukocyte common antigens. UItrastructurally, those cells showed ruffled indentations. The diffe~ntial diagnosis includes microvillous malignant lymphoma. The patient has had a four-year follow-up without relapses.