Article
Ki-1 Large Cell Lymphoma with Regressing Lesions in a Child
Registro en:
BITTENCOURT, A. C. L. et al. Ki-1 Large Cell Lymphoma with Regressing Lesions in a Child. Pediatric Dermatology, v. 9, n. 2, p. 117-122, 1992.
0736-8046
Autor
Bittencourt, Achilea Candida Lisboa
Mendonça, Nubia
Freitas, Luiz Antonio Rodrigues de
Schnitzer, Bertram
Resumen
Abstract: An 8-year-old boy was seen with a cutaneous Ki-1 anaplastic,
large cell lymphoma with multiple lesions. Some of the lesions showed
spontaneous regression. During more than seven years of disease no
systemic involvement was observed, but recurrent, self-heal~ngle sions
did appear. Histopathologic examination of five lesions revealed a variety
of findings, from an inflammatory infiltrate to a highly anaplastic pattern.
The neoplastic cells expressed Ki-1 and leukocyte common antigens. UItrastructurally,
those cells showed ruffled indentations. The diffe~ntial
diagnosis includes microvillous malignant lymphoma. The patient has
had a four-year follow-up without relapses.