Article
Capsular switching in invasive Neisseria meningitidis, Brazil
Registro en:
CASTIÑEIRAS, Terezinha M. P. P. et al. Capsular Switching in Invasive Neisseria meningitidis, Brazil. Emerging Infectious Diseases, v.18, n.8, 3p, Aug. 2012.
1080-6040
10.3201/eid1808.111344
1080-6059
Autor
Castiñeiras, Terezinha M. P. P.
Barroso, David E.
Marsh, Jane W.
Tulenko, Mary M.
Krauland, Mary G.
Rebelo, Maria C.
Harrison, Lee H.
Resumen
During the 1990s, an epidemic of B:4 Neisseria meningitidis infections affected Brazil. Subsequent increase in C:4 disease suggested B → C capsular switching. This study identified B → C switches within the sequence type 32 complex. Substantial disease related to capsular switching emphasizes the need for surveillance of circulating meningococcal strains to optimize disease control.