Article
Tracing the origin of Brazilian HTLV-1 as determined by analysis of host and viral genes.
Registro en:
ALCANTARA JUNIOR, L. C. et al. Tracing the origin of Brazilian HTLV-1 as determined by analysis of host and viral genes. AIDS, v. 20, n. 5, p. 780-782, 2006.
0269-9370
Autor
Alcantara, Luiz Carlos Júnior
Oliveira, Tulio de
Gordon, Michelle
Pybus, Oliver G.
Mascarenhas, Rita Elizabeth Moreira
Seixas, Magda Oliveira
Gonçalves, Marilda de Souza
Hlela, Carol
Cassol, Sharon
Castro Filho, Bernardo Galvão
Resumen
We compared the genetic diversity of the Brazilian human T-cell lymphotropic virus type 1 isolates with those found in KwaZulu-Natal (KZN), South Africa, and with the genetic background of the hosts. The seroprevalence rate in KZN was 1.7%. All sequences belonged to the A subgroup. The presence of South African sequences in two different clusters from Brazil, and the finding of the beta-globin haplotype in infected hosts are consistent with the transmission of this virus from southern Africa to Brazil.