Abstract A delay differential equations epidemic model of SIQR (Susceptible-Infective-Quarantined-Recovered) type, with arbitrarily distributed periods in the isolation or quarantine class, is proposed. Its essential mathematical features are analyzed. In addition, conditions that support the existence of periodic solutions via Hopf bifurcation are identified. Nonexponential waiting times in the quarantine/isolation class lead not only to oscillations but can also support stability switches.